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Aging and coronary blood flow paper accepted for publication in AJP Heart

posted Sep 24, 2014, 8:13 AM by Annie Muller
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In this study, we found that older men had an attenuated coronary blood flow responses to isometric handgrip compared to young men. Following infusion of the beta blocker propranolol, the change in coronary flow at peak handgrip exercise decreased in young men (9.7 ± 2.1 versus 2.7 ± 0.9 cm/s, P = 0.008) but not older men (3.8 ± 1.3 versus 4.2 ± 1.9 cm/s, P = 0.9). Older men also had attenuated coronary hyperemia to low dose isoproterenol. Amanda Ross was the first author and Dr. Matt Muller was the last author/ corresponding author.

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