Post date: Sep 3, 2013 12:16:46 PM
In this double-blind, placebo- controlled crossover study, we tested the hypothesis that melatonin (3 mg) would attenuate the SSNA response to mental stress (mental arithmetic). Consistent with our hypothesis, melatonin attenuated the SSNA response to mental stress. These data support the concept that melatonin elicits a generalized reduction in sympathetic nerve responses to stress.