Post date: Nov 13, 2018 1:44:40 AM
September 2018: Peripheral artery disease (PAD) is highly prevalent in older adults and is characterized by impaired walking tolerance and high risk of cardiac death. In this T1 translational project we will conduct mechanism-driven intervention studies to test how beta-1 blockade (Aim 1) and dietary nitrate supplementation in beetroot juice (Aim 2) impact walking tolerance and coronary blood flow in PAD patients age 55 to 85.