Coronary blood flow article accepted in AJP Heart and Circ Physiol

Post date: Jan 17, 2014 10:37:17 AM

In this study, we found that forehead cooling elicits a sympathetically-mediated pressor response and a reduction in coronary blood flow velocity and this effect was augmented under beta-adrenergic blockade with propranolol. The results are consistent with sympathetic activation of beta-receptor coronary vasodilation in humans, as has been demonstrated in animals.

Beta-adrenergic blockade enhances coronary vasoconstrictor response to forehead cooling.

Muller MD, Gao, Z, Patel HM, Heffernan MJ, Leuenberger UA, Sinoway LI.

IN PRESS, Am J Physiol: Heart Circ Physiol, accepted 1/16/2014.

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